I would just like to introduce the two people who are going to be doing this vicious debate. Dr. Flanigan was the principal investigator for the Southwest Oncology Group protocol that showed that resection of the primary tumor in patients with metastatic disease who were also treated with interferon had better overall survival than those patients who received interferon alone (without nephrectomy).

Dr. Dreicer from the Cleveland Clinic is going to take the opposite view, and perhaps shed some light on why we should not be doing a nephrectomy in all patients with metastatic disease. And then we'll have a panel discussion to hash out what the real truth is.

Bob.

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