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Special
Posting: March
3, 2003 Summary
of Working Group Meeting for Myeloproliferative, Myelodysplastic,
and Marrow Failure Syndromes (PDF format)
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SUMMARY OF LEUKEMIA
MEETINGS
Four State of the Science (SOTS) meetings on the leukemias have been held
since SOTS's inception in 1999. To date, meetings have been convened to
focus on the myeloproliferative disorders and mastocytosis; myelodysplastic
syndromes; acute myeloid leukemia;and acute lymphoblastic leukemia. Meetings
have covered a range of issues, from characterization of disease etiology
at the genetic and transcriptional level, to prioritizing molecular targets
for therapeutic agents, to strategies for clinical trial design and monitoring,
to addressing the clinical realities of MDR in leukemia patients at various
stages of disease to the importance of looking at MRD early in therapy,
as well as the different approaches for using MRD to direct therapy in
adults and children. The meetings provide a structured forum for interaction
among clinical investigators and basic scientists from academia, industry,
and the community, as well as representatives of patient advocacy organizations.
Overview
of State of the Science (SOTS) Implementation Working Group Meeting
For Myeloproliferative, Myelodysplastic, and Marrow Failure Syndromes -
March 3, 2003. A meeting was held in Bethesda, Maryland to develop an action
plan focusing on myeloproliferative, myelodysplastic, and marrow failure
syndromes (MPS/MDS/MFS) as mandated by a congressional statement of
January 15, 2003. An initial step in the planning process was to identify
existing resources within the National Cancer Institute (NCI) and the
National Heart Lung and Blood Institute (NHLBI) that could be utilized
as a foundation for other initiatives. Summary
of Working Group Meeting for Myeloproliferative, Myelodysplastic, and
Marrow Failure Syndromes (PDF format) summarizes
actions recommended by the Working Group to allocate funding and to
direct the development of a matrix of projects where results could
be shared and evaluated.
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